From 2000 to 2002, she starred in the Showtime drama series Resurrection Blvd. . In 2001, she played Bahraini Princess, (Sheika) Meriam Al Khalifa in the made-for-TV movie The Princess and the Marine. In 2003, she made guest appearances on episodes of Friends, CSI: Crime Scene Investigation, Law & Order: Special Victims Unit, Nip/Tuck and Charmed. Marisol's Charmed episode, "Chris-Crossed," was the show's 'highest-rated non-season-premiere episode'. In 2006, she appeared in six episodes of Cold Case and starred in the film Big Momma's House 2.