On May 25, 2017, it was reported that Roden would play the lead in the third season of Syfy's horror anthology series Channel Zero, titled Butcher's Block (originally titled Staircases), which is based on the online Creepypasta stories. She portrayed Zoe Woods, a young woman who struggles with mental illness. The show premiered on February 7, 2018. On May 31, 2017, Roden was cast as the lead in the Amazon Video horror anthology series Lore, in which she played the role of Bridget Cleary. Lore premiered on October 13, 2017.